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Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans

NCT03061916 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2017-02-23

No results posted yet for this study

Summary

Chlorhexidine is the most potent chemotherapeutic agent against mutans streptococci and dental caries, however, the incidence of side effects such as teeth discoloration, staining of restorations, undesirable taste, discoloration of tongue, dryness and burning sensation in the mouth discourage patients to use this mouth wash. Natural products are now preferred by a large proportion of the population and have been reported to possess antimicrobial activity.These products have recently been shown to be a good alternative to synthetic chemical substances for caries prevention like Cinnamon and Ginger. The aim of this study is to compare the antimicrobial effects of aqueous extracts of cinnamon 20% and ginger 20% in comparison to chlorhexidine gluconate 0.2% on oral streptococcus mutans

Conditions

  • Dental Caries

Interventions

DIETARY_SUPPLEMENT

Cinnamon

Cinnamon 20% will be given to participants after baseline collection of saliva

DIETARY_SUPPLEMENT

Ginger

Ginger 20% will be given to participants after baseline collection of saliva

DRUG

Chlorhexidine Gluconate

Chlorhexidine Gluconate will be given to participants after baseline collection of saliva

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Heba Hamza, PhD · Cairo university, Professor of conservative dentistry

  • Mai Mamdouh, PhD · Cairo university, lecturer of conservative dentistry

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-31
Primary Completion
2017-05-01
Completion
2017-11-01

Countries

  • Egypt

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03061916 on ClinicalTrials.gov