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CPT-fMRI Study for PTSD

NCT03229915 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 68

Last updated 2023-02-15

No results posted yet for this study

Summary

Posttraumatic stress disorder (PTSD) is prevalent mental illness (\~9% life-time) that results from exposure to trauma. As it is associated with vastly heterogeneous origins, accurate diagnosis and optimal treatment strategies are sometimes very difficult to achieve. No known biomarker exists, which makes it difficult to assess treatment response and functional outcomes. The recent brain imaging studies have suggested that PTSD patients show abnormal brain connectivity measured by functional magnetic resonance imaging (fMRI). The investigators propose that cognitive processing therapy may ameliorate this functional connectivity abnormality which may be related with their symptomatic improvement.

Conditions

  • Stress Disorders, Post-Traumatic

Interventions

BEHAVIORAL

cognitive processing therapy

Group therapy for PTSD patients

Sponsors & Collaborators

  • Workers Compensation Board of Manitoba

    collaborator UNKNOWN

  • University of Manitoba

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-01
Primary Completion
2022-09-30
Completion
2022-09-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03229915 on ClinicalTrials.gov