MedTrace Logo

Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study)

NCT03228771 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2018-09-24

No results posted yet for this study

Summary

Despite the numerous studies describing the benefits of PRGF (plasma rich in growth factors) and Statins separately , there has been a lack of clinical investigation into the simultaneous use of these agents in socket augmentation. Therefore the main objective of this study is to evaluate socket bone dimensions and quality following the use of PRGF derived fibrin scaffold as a carrier for Atorvastatin in socket augmentation clinically and histomorphometrically.

Conditions

  • Socket Preservation

Interventions

DRUG

PRGF/ATV

Atorvastatin loaded in PRGF fibrin scaffold

DRUG

ATV gel

Atorvastatin loaded in methyl cellulose gel

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Khaled A Ghaffar, Professor · Ain Shams University

  • Ola M Ezzatt, Lecturer · Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2018-06-30
Completion
2018-08-15

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03228771 on ClinicalTrials.gov