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Relationship Between Gut Microbiota And Anemia In Patients With Chronic Renal Failure

NCT03220685 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2025-07-03

No results posted yet for this study

Summary

The human intestinal tract harbours a diverse and complex microbial community which plays a central role in human health. It has been estimated that our gut contains in the range of 1000 bacterial species and 100-fold more genes than are found in the human genome . This community is commonly referred to as our hidden metabolic 'organ' due to their immense impact on human wellbeing, including host metabolism, physiology, nutrition and immune function. It is now apparent that our gut microbiome coevolves with us and that changes to this population can have major consequences, both beneficial and harmful, for human health. Indeed, it has been suggested that disruption of the gut microbiota (or dysbiosis) can be significant with respect to pathological intestinal conditions such as obesity and malnutritio, systematic diseases such as diabetes and chronic inflammatory diseases such as inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD) .

The role of the gut microbiome in human health and disease is becoming clearer thanks to high throughput sequencing technologies (HTS) as well as parallel recent developments in non genomic techniques.

Conditions

  • Gut Micrbota and Its Relation to Anemia of CKD Patients

Interventions

BIOLOGICAL

Stool analysis

Bacterial extraction in faeces by repeated fractional centrifugation to obtain bacterial mass and DNA sequencing.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Samir Kamal, Dr · Lecturer

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-25
Primary Completion
2022-01-01
Completion
2022-03-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03220685 on ClinicalTrials.gov