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Implications of MEDIcal Low Dose RADiation Exposure - BReast Cancer Acute Coronary Events

NCT03211442 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 7000

Last updated 2024-02-28

No results posted yet for this study

Summary

MEDIRAD-BRACE aims to determine the relationship between 3D dose distributions in cardiac structures and the risk of acute coronary events (ACE) and other cardiac complications in breast cancer (BC) patients to develop and externally validate multivariable Normal Tissue Complication Probability (NTCP) models to assess the risk of ACE in individual patients based on cardiac dose metrics in the first 10 years after BC radiotherapy.

Conditions

  • Breast Cancer Female
  • Acute Coronary Events
  • Cardiac Complications

Interventions

RADIATION

Radiotherapy

Breast cancer patients treated with radiotherapy

Sponsors & Collaborators

  • The Netherlands Cancer Institute

    collaborator OTHER

  • Technical University of Munich

    collaborator OTHER

  • Institut de Radioprotection et de Surete Nucleaire

    collaborator OTHER_GOV

  • University Medical Center Groningen

    lead OTHER

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-01
Primary Completion
2020-08-01
Completion
2022-06-01

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03211442 on ClinicalTrials.gov