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Sourdough Bakery Products and Digestive Function

NCT03207516 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2017-07-02

No results posted yet for this study

Summary

In a double-blind, randomised crossover study, two sourdough croissants (SC) or two brewer's yeast croissants (BC) were served to 17 (9 F; Age range 18-40; BMI range 18-24 kg/m2) healthy subjects to evaluate the effects of their ingestion on postprandial gastrointestinal functions. Hydrogen breath test was performed to measure H2 production after SC and BC ingestion. Gastric volume was evaluated by Magnetic Resonance(MR) Imaging to calculate gastric emptying rate in the 3-hour interval following croissant ingestion. Palatability and postprandial gastrointestinal symptoms and perceptions over a 4-h period after the meal were evaluated by visual analogue scale (VAS). In addition, in the 3-hour interval, blood samples were drawn to measure serum glucose levels. The area under the curve (AUC) was employed to evaluate global kinetics of all parameters and the T-test was used to evaluate differences between groups.

Conditions

  • Dyspepsia

Interventions

DIETARY_SUPPLEMENT

Sourdough --> Brewer's Yeast

Impact of bakery products with sourdough or brewer's yeast on digestive function

DIETARY_SUPPLEMENT

Brewer's Yeast --> Sourdough

Impact of bakery products with sourdough or brewer's yeast on digestive function

Sponsors & Collaborators

  • Federico II University

    collaborator OTHER

  • Fresystem S.p.A.

    collaborator UNKNOWN

  • Irccs Sdn

    lead OTHER

Principal Investigators

  • Emanuele Nicolai · Irccs Sdn

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-07-22
Primary Completion
2015-04-28
Completion
2015-04-28

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03207516 on ClinicalTrials.gov