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Topical Antibiotic Prophylaxis for Eyelids

NCT03199911 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 401

Last updated 2020-07-21

Study results available
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Summary

The investigators propose a prospective randomized control trial testing the hypothesis that routine topical antibiotic prophylaxis does not significantly reduce the rate of infection after eyelid surgery.

Conditions

  • Antibiotic Side Effect
  • Eyelid; Wound
  • Eyelid Diseases
  • Surgical Wound Infection
  • Surgical Wound, Recent
  • Surgical Incision
  • Skin Cancer Face
  • Antibiotic Allergy
  • Surgical Site Infection

Interventions

DRUG

Topical Antibiotic Product

Topical antibiotic ointment will be erythromycin or bacitracin. If the patient cannot obtain either (e.g. lack of availability at the pharmacy), bacitracin polymyxin will be prescribed. Allergy to all 3 study drugs means that a patient will be excluded from the study.

DRUG

Topical Non-Antibiotic Ointment

Mineral oil/petrolatum-based artificial tear ointment.

Sponsors & Collaborators

Principal Investigators

  • Robert Kersten, MD · University of California, San Francisco

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-02
Primary Completion
2019-11-14
Completion
2019-11-14
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03199911 on ClinicalTrials.gov