Dental Stem Cells and Bone Tissue Engineering (CELSORDINO)
NCT03194451 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2017-06-23
Summary
The main limitation in bone regeneration is the lack of vascularization of the newly shaped tissue. The main objective of this project is to check if the simultaneous differentiation of dental mesenchymal stem cells toward osteoblastic and endothelial lineage permits to obtain a new pre-vascularized tissue engineered bone construct.
We will then evaluate the boosting effect of the conditionned medium on cell differentiation and production of a prevascularized bone construct.
Conditions
- Tooth, Impacted
Interventions
- OTHER
-
non-interventional study
teeth collection
Sponsors & Collaborators
-
Central Hospital, Nancy, France
lead OTHER
Principal Investigators
-
Vanessa MOBY, DD, PhD · IMoPA, UMR-CNRS 7365 CNRS-UL, Medicine Faculty
Eligibility
- Min Age
- 13 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-07-10
- Primary Completion
- 2017-08-20
- Completion
- 2019-07-10
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