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Vaginal Cuff Brachytherapy Followed by Chemotherapy in Endometrial Cancer

NCT03189446 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 39

Last updated 2024-03-08

Study results available
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Summary

The purpose of this study is to determine the feasibility of treatment in patients with high risk endometrial cancer treated by vaginal cuff brachytherapy followed by 3 cycles of dose dense paclitaxel and carboplatin chemotherapy.

Conditions

Interventions

RADIATION

Vaginal Cuff Brachytherapy

Within 12 weeks of surgery. Either LDR or HDR brachytherapy will be permitted

DRUG

Carboplatin

Carboplatin IV on day 1 of a 21 day cycle for 3 cycles

DRUG

Paclitaxel

Paclitaxel IV on days 1,8 and 15 of a 21 day cycle for 3 cycles

Sponsors & Collaborators

  • University of Oklahoma

    lead OTHER

Principal Investigators

  • Kathleen Moore, MD · Stephenson Cancer Center

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-02
Primary Completion
2019-12-13
Completion
2021-10-06
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03189446 on ClinicalTrials.gov