Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

NCT05296421 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2026-05-04

No results posted yet for this study

Summary

This clinical trial investigates the nutrients pancreatic cancers depend on in which to survive and the processes these tumors use (metabolism) to obtain these nutrients. Giving U-13C-glucose during surgery may allow doctors to trace the metabolic activity of pancreatic cancer in research experiments done in the laboratory. These experiments may help researchers understand how cancer cells manage their nutrients when compared to normal pancreatic cells.

Conditions

Interventions

PROCEDURE

Biopsy

Undergo biopsy

PROCEDURE

Therapeutic Conventional Surgery

Undergo surgery

OTHER

Uniformly-labeled [13C]glucose

Given IV

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH
  • Rutgers, The State University of New Jersey

    lead OTHER

Principal Investigators

  • Howard S Hochster, MD · Rutgers Cancer Institute of New Jersey

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-14
Primary Completion
2027-03-01
Completion
2027-07-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05296421 on ClinicalTrials.gov