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The Effect of Manipulation of the Cervical Spine on Pain Biomarkers

NCT03176654 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2019-08-01

Study results available
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Summary

This study evaluates the effect of high-velocity low-amplitude thrust (HVLAT) manipulation to the cervical spine on neuropeptide expression as determined by the plasma concentration of oxytocin, neurotensin, orexin A and cortisol; and Examine the effect of HVLAT manipulation on pain perception in symptomatic females with non-specific mechanical cervical spine pain

Conditions

  • Neck Pain, Posterior

Interventions

PROCEDURE

HVLAT manipulation

HVLAT will be performed 10 minutes after the first blood draw.

PROCEDURE

Sham HVLAT manipulation

Sham HVLAT will be performed 10 minutes after the first blood draw.

Sponsors & Collaborators

  • Loma Linda University

    lead OTHER

Principal Investigators

  • Everett Lohman, D.Sc. · Loma Linda University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-08-15
Primary Completion
2016-09-20
Completion
2016-09-20

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03176654 on ClinicalTrials.gov