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Platelet-rich Fibrin on Nerve Regeneration After Bilateral Sagittal Split Osteotomy

NCT03159338 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2017-12-07

No results posted yet for this study

Summary

Patients who have mandibular deformity and will undergo bilateral sagittal split osteotomy will be included in the study.One side of the osteotomies randomly will be considered as study group and another side as a control group.In the study group , platelet rich fibrin will be placed after osteotomy and before rigid fixation.In the control group, fixation will be done without Platelet-rich Fibrin (PRF).Neurosensory disturbance will be evaluated 6 and 12 months after surgeries.

Conditions

  • Paresthesia
  • Anesthesia, Local
  • Neurosensory Disorder

Interventions

BIOLOGICAL

Platelet rich fibrin

Platelet rich fibrin will be prepared by taking 20 cc blood and centrifugation with 28000 rpm.

BIOLOGICAL

Placebo

In control group , after spliting the osteotomy site before fixation a placebo gel will be placed

Sponsors & Collaborators

  • Shahid Beheshti University of Medical Sciences

    collaborator OTHER

  • Shiraz University of Medical Sciences

    lead OTHER

Principal Investigators

  • Reza Tabrizi, DMD · Shiraz University of Medical Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-01
Primary Completion
2018-05-30
Completion
2018-09-30

Countries

  • Iran

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03159338 on ClinicalTrials.gov