The Modular Protocol for Mental Health (MPMH)

Summary

Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc. These 'diagnosis-specific' treatments work well for people whose problems fit neatly into a single diagnosis. However, they work far less well for people with complex problems involving multiple diagnoses, and 50% of patients fail to respond well to these existing treatments.

The purpose of this study is to test a new psychological treatment for anxiety and mood problems (the Modular Protocol for Mental Health \[MPMH\]). Instead of focusing on any single diagnosis, MPMH combines the best treatment techniques into 10 modules to target problems common across all of the different mood and anxiety diagnoses (e.g., intense emotions, negative thinking, upsetting memories, distressing habits). MPMH should therefore be a better treatment for the large numbers of individuals whose problems do not fit neatly into a single diagnosis and for whom any treatments targeting a single diagnosis would leave significant difficulties unaddressed.

Conditions

• Major Depressive Disorder
• Generalized Anxiety Disorder
• Posttraumatic Stress Disorder
• Social Anxiety Disorder
• Panic Disorder
• Agoraphobia
• Obsessive-Compulsive Disorder
• Illness Anxiety Disorder

Interventions

BEHAVIORAL

The Modular Protocol for Mental Health

This intervention is based on evidence-based cognitive-behavioural approaches to psychological disorders and offers a flexible approach to treatment delivery that targets the maladaptive processes common to mood and anxiety disorders.

BEHAVIORAL

Treatment-as-usual

This intervention will consist of psychological therapies delivered by high-intensity therapists or clinical psychologists.

Sponsors & Collaborators

• Cambridgeshire and Peterborough NHS Foundation Trust

  collaborator OTHER

• Medical Research Council Cognition and Brain Sciences Unit

  lead OTHER_GOV

Principal Investigators

• Tim Dalgleish, PhD · Medical Research Council Cognition and Brain Sciences Unit

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-07-18

Primary Completion

2020-07-31

Completion

2020-07-31

Countries

• United Kingdom

Study Locations