B2 Adrenergic Receptor Gene Polymorphism in Bronchial Asthma
NCT03118869 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 75
Last updated 2017-08-28
Summary
The b2-adrenoceptor (b2AR) mediates the physiological responses in the airway, which include bronchodilation, bronchoprotection. The b2-adrenoceptor (b2AR) mediates the physiological responses in the airway, which include bronchodilation, bronchoprotection, Enhanced mucociliary clearance.
The b2AR gene is located on chromosome 5q31-q32, a region that is genetically linked to asthma and related phenotypes. There are three best known polymorphisms in the coding region of the b2AR gene that can modulate the function of the receptor.
Conditions
- Gene Abnormality
- Asthma
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Aliae Mohamed-Hussein · Professor of Pulmonology- Faculty of Medicine-Assiut University
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-04-01
- Primary Completion
- 2017-10-01
- Completion
- 2017-10-30
Countries
- Egypt
Study Locations
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