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Nitric Oxide, LPS and the Pathogenesis of Asthma Phase 1

NCT00671229 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 420

Last updated 2015-04-14

No results posted yet for this study

Summary

The purpose of the study is to determine the role of nitric oxide (NO) in asthma. We determine the effect of promoter polymorphisms in the gene for the NO producing enzyme, nitric oxide synthase (NOS2), on exhaled NO in healthy African Americans and Caucasians. We compare exhaled NO levels between African Americans and Caucasians. Information on race or ethnicity, serum samples, blood pressure, exhaled breath condensate and health questionnaires will be collected.

Conditions

Sponsors & Collaborators

  • Sandler Program for Asthma Research

    collaborator OTHER

  • National Institute of Environmental Health Sciences (NIEHS)

    lead NIH

Principal Investigators

  • Marc C Levesque, M.D., PhD · Duke University

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-05-31
Primary Completion
2008-06-30
Completion
2008-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00671229 on ClinicalTrials.gov