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Irrigating Fluid and Blood Coagulation

NCT03105180 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2017-04-07

No results posted yet for this study

Summary

Irrigating fluid absorbed during the endoscopic surgery may alter whole blood coagulation. However, little is known about the dose-response relationships of hemodilution. The investigators have therefore performed the present study to measure the effect of a mixture of 2.7% sorbitol-0.54% mannitol solution on the coagulation pathway according to the hemodilution level using a rotational thromboelastometry (ROTEM®) tests.

Conditions

  • Blood Coagulation Disorder

Interventions

OTHER

A mixture of 2.7% sorbitol-0.54% mannitol solution

Venous blood was taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 10%, 20%, and 40%) using a mixture of 2.7% sorbitol-0.54% mannitol solution.

Sponsors & Collaborators

  • Seoul National University Bundang Hospital

    lead OTHER

Principal Investigators

  • Hyo-Seok Na, PhD · Seoul National University Bundang Hospital

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-10
Primary Completion
2017-03-29
Completion
2017-03-29

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03105180 on ClinicalTrials.gov