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COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation

NCT03088150 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 618

Last updated 2022-12-20

No results posted yet for this study

Summary

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Conditions

Interventions

PROCEDURE

Thermal ablation

Patients will undergo either radiofrequency ablation (RFA) or microwave ablation (MWA).

PROCEDURE

Surgical resection

In case of randomization to surgical resection, the surgeon will remove all target lesions as well as all additional unablatable lesions.

Sponsors & Collaborators

  • Medtronic - MITG

    collaborator INDUSTRY

  • Amsterdam UMC, location VUmc

    lead OTHER

Principal Investigators

  • MR Meijerink, MD, PhD · VU University Medical Center, Amsterdam, NL

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-13
Primary Completion
2024-07-31
Completion
2024-12-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03088150 on ClinicalTrials.gov