Transplantation of Autologous Peripheral Blood Mononuclear Cells for Amyotrophic Lateral Sclerosis
NCT03085706 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2018-02-09
Summary
To assess the safety of peripheral blood mononuclear cell transplantation into the subarachnoid space for the treatment of amyotrophic lateral sclerosis.
Conditions
Interventions
- BIOLOGICAL
-
PBMC autotransplantation
Fourteen amyotrophic lateral sclerosis (ALS) patients are received peripheral blood mononuclear cell (PBMC) autotransplantation.
Sponsors & Collaborators
-
The First Affiliated Hospital of Dalian Medical University
lead OTHER
Principal Investigators
-
Jing Liu, Ph.D. · The First Affiliated Hospital of Dalian Medical University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 31 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-10-31
- Primary Completion
- 2012-12-31
- Completion
- 2013-06-30
Countries
- China
Study Locations
More Related Trials
-
Biological Treatment of Amyotrophic Lateral Sclerosis
NCT02193893 ·Status: UNKNOWN ·Phase: PHASE1
-
Explore Neuroprotective Effect of Lipoic Acid in Amyotrophic Lateral Sclerosis
NCT04518540 ·Status: UNKNOWN ·Phase: NA
-
Compassionate Treatment : An Exploratory Clinical Trial to Assess Treatment of Amyotrophic Lateral Sclerosis
NCT02383654 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Trial on the Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis
NCT00855400 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dose Escalation and Safety Study of Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis
NCT01730716 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Trial on The Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (Extension CMN/ELA)
NCT01254539 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response
NCT00397423 ·Status: COMPLETED ·Phase: PHASE2
-
Safety/Efficacy Study for the Treatment of Amyotrophic Lateral Sclerosis
NCT01082653 ·Status: SUSPENDED ·Phase: PHASE1
-
Treatment of Intravenous Infusion Plasma in Amyotrophic Lateral Sclerosis
NCT04454840 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Clinical Trial on the Use of Cell Therapy in the Treatment of Patients With Amyotrophic Lateral Sclerosis
NCT04849065 ·Status: UNKNOWN ·Phase: PHASE2
-
Randomized, Double-blind, Safety and Efficacy of Recombinant Human Erythropoietin in Amyotrophic Lateral Sclerosis
NCT03835507 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Autologous Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT01777646 ·Status: COMPLETED ·Phase: PHASE2
-
Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response
NCT00753571 ·Status: UNKNOWN ·Phase: PHASE2
-
Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS)
NCT01142856 ·Status: COMPLETED ·Phase: PHASE1
-
The Clinical Trial on the Use of Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis
NCT01494480 ·Status: UNKNOWN ·Phase: PHASE2
-
Escalated Application of Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis Patients
NCT02987413 ·Status: COMPLETED ·Phase: PHASE1
-
Autologous Multipotent Mesenchymal Stromal Cells in the Treatment of Amyotrophic Lateral Sclerosis
NCT03828123 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral Sclerosis
NCT02872142 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate the Safety and Efficacy of Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral Sclerosis
NCT06493279 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intrathecal Injection for ALS
NCT05003921 ·Status: SUSPENDED ·Phase: PHASE1
-
Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis
NCT02479802 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Deep Cervical Lymph Node-vein Bypass Surgery in ALS Amyotrophic Lateral Sclerosis
NCT06351735 ·Status: NOT_YET_RECRUITING
-
Effect of Intrathecal Administration of Hematopoietic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT01933321 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis
NCT02286011 ·Status: UNKNOWN ·Phase: PHASE1
-
Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis
NCT01348451 ·Status: UNKNOWN ·Phase: PHASE1