Evaluation of [18F]MNI-952 as a Potential PET Radioligand for Imaging Tau Protein in the Brain
NCT03080051 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2017-10-06
Summary
The overall goal of this imaging trial is to evaluate \[18F\]MNI-952 (also known as \[18F\]UCB-K), a tau targeted PET radioligand.
Conditions
- Progressive Supranuclear Palsy
- Alzheimer Disease
- Healthy Volunteers
Interventions
- DRUG
-
[18F]MNI-952
Subjects will undergo PET imaging using \[18F\]MNI-952, a PET radioligand for imaging tau.
- DRUG
-
[18F]Florbetapir
Subjects with Alzheimer's disease will receive a \[18F\]florbetapir scan to compare distribution of tau in the brain compared to that of \[18F\]MNI-952.
Sponsors & Collaborators
-
Molecular NeuroImaging
lead OTHER
Principal Investigators
-
Jennifer Madonia, PA-C · Molecular NeuroImaging
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2017-03-06
- Completion
- 2017-03-06
Countries
- United States
Study Locations
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