The Prehospital Selection of Acute Stroke Patients

Summary

The aim of this study is to develop and validate a simple prehospital stroke scale, which would predict the presence of large vessel occlusion (LVO) in patients with acute stroke. This study prospectively evaluates the predictive value of a new simple pre-hospital scale (FAST PLUS test) for the presence of large vessel occlusion in anterior intracranial circulation. The FAST PLUS test consists of two parts: the first is the well-known FAST test, which is employed in all possible cases of stroke occurrence. This test consists of the following items: Speech (scored 0-1), Facial palsy (0-1), any failure of Arm motor function (0-1), and Time (0-1). The second part of FAST PLUS test evaluates only the presence of severe arm or leg motor deficit (scored 0-1) and unilateral occurrence of its motor function deficit (scored 0-1).

The FAST PLUS test will be used prospectively at the place of stroke onset by trained medical emergency technicians. The first objective of study is to evaluate the sensitivity, specificity, and the positive and negative predictive value of the test which relate to the presence of occlusion of intracranial artery (intracranial carotid artery, T occlusion and occlusion of Middle Cerebral artery segment M1 and M2). CT angiography can only diagnose the LVO.

The second objective of this study is to assess inter-rater variability among stroke specialists and emergency technicians, concerning the presence of severe motor arm or leg deficit.

The third objective : After implementation of the FAST TEST to clinical practice, we aim to achieve the acceleration of transport time in FAST PLUS positive patients via direct transport to Comprehensive Stroke Center to mechanical thrombectomy.

Conditions

• Stroke

Interventions

DIAGNOSTIC_TEST

FAST PLUS test

FAST PLUS test consists of two parts: the first one is the standard FAST test, which evaluates Speech (0-1), Facial palsy (0-1), Arm motor function (0-1), Time (0-1). The second part of the FAST PLUS test evaluates only the presence of severe arm or leg motor deficit (0-1), and unilateral occurrence of this motor function deficit (0-1).

Sponsors & Collaborators

• University of Ostrava

  collaborator OTHER

• Agel Research and Training Institute

  collaborator OTHER

• Emergency Medical Service Ostrava, Ostrava, Czech Republic

  collaborator UNKNOWN

• Municipal Hospital Ostrava, Ostrava, Czech Republic

  collaborator UNKNOWN

• St. Anne's University Hospital Brno, Czech Republic

  collaborator OTHER

• Angels Initiative, European Stroke Organisation, Czech branch

  collaborator UNKNOWN

• University Hospital Ostrava

  lead OTHER

Principal Investigators

• Michal Bar, Ass.Prof.,MD,PhD · University Hospital Ostrava

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-03-01

Primary Completion

2018-08-31

Completion

2018-10-01

Countries

• Czechia

Study Locations