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Helical CT, PET/CT, MRI, and CBCT Alone or in Combination in Predicting Jaw Invasion in Patients With Oral Cancer

NCT03053960 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 8

Last updated 2025-04-30

Study results available
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Summary

This clinical trial studies how well helical computed tomography (CT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and cone beam computed tomography (CBCT) work alone or in combination in predicting whether tumor cells have spread to the jaw bone (jaw invasion) in patients with oral cancer. Imaging, such as helical CT, PET/CT, MRI, and CBCT, may help find out how far cancer has spread. Accurate prediction of the presence or absence of jaw invasion may help create a better surgical treatment plan for patients with oral cancer.

Conditions

  • Oral Cavity Squamous Cell Carcinoma

Interventions

DEVICE

Computed Tomography

Undergo helical CT scan

DEVICE

Positron Emission Tomography and Computed Tomography Scan

Undergo PET/CT scan

DEVICE

Cone-Beam Computed Tomography

Undergo CBCT scan

DEVICE

Magnetic Resonance Imaging

Undergo MRI scan

PROCEDURE

Therapeutic Conventional Surgery

Undergo resection of tumor

PROCEDURE

Histopathologic Examination

Correlative studies

Sponsors & Collaborators

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    lead OTHER

Principal Investigators

  • Lionel Gold, MD · Sidney Kimmel Cancer Center at Thomas Jefferson University

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-11-24
Primary Completion
2018-11-01
Completion
2018-11-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03053960 on ClinicalTrials.gov