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Short-term Effects of Supplemental Oxygen in Patients With IPF

NCT03050255 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 53

Last updated 2018-12-04

No results posted yet for this study

Summary

Although exercise-induced desaturation is frequently observed in patients with idiopathic pulmonary fibrosis (IPF) short-term effects of supplemental oxygen during walking have not been investigated yet. Given, that walking ability is the most important activity of daily life, the aim of our study is to investigate the effects of supplemental oxygen on endurance walking capacity in hypoxemic IPF patients. In this study patients will perform 3 endurance shuttle walk tests (ESWTs) at 85% of their individual peak performance using medical air (=compressed room air, 2 liters/minute), 2 liters/minute oxygen, 4 liters/minute Oxygen in a double-blinded fashion and random order.

Since there are only limited pharmacological treatment options for IPF patients, this study may help to provide novel information about the short-term effects of supplemental oxygen. Furthermore it may help to investigate possibilities to optimize oxygen therapy in order to facilitate patients´ participation in activities of daily life and not at least to improve patients´ quality of life.

Conditions

  • Idiopathic Pulmonary Fibrosis (IPF)

Interventions

OTHER

Medical air

OTHER

Oxygen (2Liter/min)

OTHER

Oxygen (4Liter/min)

Sponsors & Collaborators

  • Linde AG

    collaborator INDUSTRY

  • Schön Klinik Berchtesgadener Land

    lead OTHER

Principal Investigators

  • Klaus Kenn, Prof. · Schoen Klinik Berchtesgadener Land

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-11-30
Primary Completion
2018-03-31
Completion
2018-03-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03050255 on ClinicalTrials.gov