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Evaluation of Automatic Oxygen Flow Titration During Walking in Patients With COPD

NCT02150434 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2014-05-29

No results posted yet for this study

Summary

The aim of the current study was to evaluate a new system (FreeO2) that automatically titrates oxygen flow to maintain stable SpO2, in patients with moderate or severe chronic obstructive pulmonary disease during exercise. The investigators hypothesized that continuous automatic adjustment of the oxygen flows during exercise would better maintain patients within the oxygenation target, reduce episodes of desaturation and hyperoxia and would improve walking exercise tolerance in comparison with fixed levels of low-flow oxygen and with compressed air breathing.

Conditions

  • COPD
  • Exercise
  • Endurance Shuttle Walking Test (Exercise at 85% of Maximal Shuttle Walking Test)

Interventions

DEVICE

Automated oxygen titration

Automated oxygen titration every second to maintain stable SpO2 at a predefined value (94% in the present study)

DRUG

Compressed air

compressed air delivered at a fixed flow of 2 L/min

DRUG

Oxygen constant flow

oxygen delivered at a fixed flow of 2L/min

Sponsors & Collaborators

  • Fonds de la Recherche en Santé du Québec

    collaborator OTHER_GOV

  • Canada Foundation for Innovation

    collaborator OTHER

  • Laval University

    lead OTHER

Principal Investigators

  • François Lellouche, MD PhD · Centre de recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-11-30
Primary Completion
2012-05-31
Completion
2013-06-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02150434 on ClinicalTrials.gov