Trial Outcomes & Findings for Manikin To Patient Intubation: Does It Translate? (NCT NCT03046966)

NCT ID: NCT03046966

Last Updated: 2021-07-07

Results Overview

Residents reported the number of successful intubation encounters they performed during their one month long NICU rotation. A successful intubation encounter is an intubation procedure where the resident successfully placed the the endotracheal tube (ETT) through the vocal cords into the trachea. Placement was confirmed with xray, chest auscultation, improvement in heart rate, and CO2 detectors.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

102 participants

Primary outcome timeframe

1 month- neonatal intensive care unit (NICU) rotation

Results posted on

2021-07-07

Participant Flow

102 residents were approached for enrollment. 102 residents were consented and randomized to intervention or control based on month of NICU rotation.

Participant milestones

Participant milestones
Measure
Intervention Control: No Training
Does not receive hands-on intubation training in the Simulation Lab. Intervention: Control No Training: • Does not receive simulation training with PI. Only standard training.
Intervention: Receives Training
Receives hands-on intubation training in the Simulation Lab. Intervention: Receives Training: • Complete a Hands-on Intubation in the Simulation Lab with PI instructing: * Using state of the art technology, a Storz C-MAC video laryngoscope * Identifying anatomical landmarks * Practice on the manikin until intubation occurs within 15 seconds
Overall Study
STARTED
51
51
Overall Study
COMPLETED
51
51
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Manikin To Patient Intubation: Does It Translate?

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Control Group
n=51 Participants
Control: No Training Residents received standard training consisting of intern orientation.
Intervention Group
n=51 Participants
Intervention Group: Received individualized with a neonatologist at the beginning of the NICU rotation utilizing video laryngoscope and a neonatal mannequin. These residents also received standard training at intern orientation.
Total
n=102 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Age, Categorical
Between 18 and 65 years
51 Participants
n=39 Participants
51 Participants
n=41 Participants
102 Participants
n=35 Participants
Age, Categorical
>=65 years
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Sex: Female, Male
Female
34 Participants
n=39 Participants
33 Participants
n=41 Participants
67 Participants
n=35 Participants
Sex: Female, Male
Male
17 Participants
n=39 Participants
18 Participants
n=41 Participants
35 Participants
n=35 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
3 Participants
n=39 Participants
3 Participants
n=41 Participants
6 Participants
n=35 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
48 Participants
n=39 Participants
48 Participants
n=41 Participants
96 Participants
n=35 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Region of Enrollment
United States
51 Participants
n=39 Participants
51 Participants
n=41 Participants
102 Participants
n=35 Participants
Level of Training (year)
First year
30 Participants
n=39 Participants
36 Participants
n=41 Participants
66 Participants
n=35 Participants
Level of Training (year)
Second year
14 Participants
n=39 Participants
5 Participants
n=41 Participants
19 Participants
n=35 Participants
Level of Training (year)
Third year
7 Participants
n=39 Participants
8 Participants
n=41 Participants
15 Participants
n=35 Participants
Level of Training (year)
Fourth Year
0 Participants
n=39 Participants
2 Participants
n=41 Participants
2 Participants
n=35 Participants
Comfort with Intubation
Not very comfortable
22 Participants
n=39 Participants
24 Participants
n=41 Participants
46 Participants
n=35 Participants
Comfort with Intubation
Somewhat comfortable
12 Participants
n=39 Participants
10 Participants
n=41 Participants
22 Participants
n=35 Participants
Comfort with Intubation
Neutral
9 Participants
n=39 Participants
7 Participants
n=41 Participants
16 Participants
n=35 Participants
Comfort with Intubation
Comfortable
8 Participants
n=39 Participants
10 Participants
n=41 Participants
18 Participants
n=35 Participants
Comfort with Intubation
Very comfortable
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Baseline Successful Intubation Rate
0-25%
9 Participants
n=39 Participants
9 Participants
n=41 Participants
18 Participants
n=35 Participants
Baseline Successful Intubation Rate
25-50%
6 Participants
n=39 Participants
3 Participants
n=41 Participants
9 Participants
n=35 Participants
Baseline Successful Intubation Rate
50-75%
12 Participants
n=39 Participants
8 Participants
n=41 Participants
20 Participants
n=35 Participants
Baseline Successful Intubation Rate
75-100%
6 Participants
n=39 Participants
9 Participants
n=41 Participants
15 Participants
n=35 Participants
Baseline Successful Intubation Rate
Not Applicable
18 Participants
n=39 Participants
22 Participants
n=41 Participants
40 Participants
n=35 Participants

PRIMARY outcome

Timeframe: 1 month- neonatal intensive care unit (NICU) rotation

Residents reported the number of successful intubation encounters they performed during their one month long NICU rotation. A successful intubation encounter is an intubation procedure where the resident successfully placed the the endotracheal tube (ETT) through the vocal cords into the trachea. Placement was confirmed with xray, chest auscultation, improvement in heart rate, and CO2 detectors.

Outcome measures

Outcome measures
Measure
Control Group
n=93 Intubation Encounters
Control: No Training Residents received standard training consisting of intern orientation.
Intervention Group
n=119 Intubation Encounters
Intervention Group: Received individualized with a neonatologist at the beginning of the NICU rotation utilizing video laryngoscope and a neonatal mannequin. These residents also received standard training at intern orientation.
Successful Intubation Encounters on Live Neonates
1.02 Successful Intubation Encounters
Standard Error 0.167
1.18 Successful Intubation Encounters
Standard Error 0.183

SECONDARY outcome

Timeframe: 1 month- NICU rotation

Population: Six residents in the Control group did not report the number of successful intubation encounters completed with only one attempt.

Each resident reported the number of successful intubation encounters requiring one attempt on live infants during their NICU rotation. An intubation attempt occurs any time the laryngoscope enters the neonate's mouth. There can be multiple intubation attempts in one intubation encounter. However this outcome focuses on intubation encounters where the neonate was intubated on the first attempt by the resident.

Outcome measures

Outcome measures
Measure
Control Group
n=45 Participants
Control: No Training Residents received standard training consisting of intern orientation.
Intervention Group
n=51 Participants
Intervention Group: Received individualized with a neonatologist at the beginning of the NICU rotation utilizing video laryngoscope and a neonatal mannequin. These residents also received standard training at intern orientation.
Successful Intubations on the First Attempt
0.578 Successful First Attempt Intubations
Standard Error 0.133
0.840 Successful First Attempt Intubations
Standard Error 0.161

SECONDARY outcome

Timeframe: 1 month- NICU rotation

The mean number of intubation encounters performed by each resident during their NICU rotation was compared between the Control and Intervention groups.

Outcome measures

Outcome measures
Measure
Control Group
n=51 Participants
Control: No Training Residents received standard training consisting of intern orientation.
Intervention Group
n=51 Participants
Intervention Group: Received individualized with a neonatologist at the beginning of the NICU rotation utilizing video laryngoscope and a neonatal mannequin. These residents also received standard training at intern orientation.
Total Number of Intubation Encounters Performed by Each Resident During Their NICU Rotation
1.82 Intubation Encounters
Standard Error 0.189
2.33 Intubation Encounters
Standard Error 0.214

SECONDARY outcome

Timeframe: 1 month- NICU rotation

All study residents intubated the mannequin before and after their NICU rotation. The total time of the mannequin intubation encounter was recorded. The difference in the time from end of the NICU rotation and the baseline time (beginning of the NICU rotation) was calculated.

Outcome measures

Outcome measures
Measure
Control Group
n=51 Participants
Control: No Training Residents received standard training consisting of intern orientation.
Intervention Group
n=51 Participants
Intervention Group: Received individualized with a neonatologist at the beginning of the NICU rotation utilizing video laryngoscope and a neonatal mannequin. These residents also received standard training at intern orientation.
Change in Time to Intubate the Mannequin
18.6 Seconds
Standard Error 9.61
37.6 Seconds
Standard Error 8.7

Adverse Events

Intervention Control: No Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Intervention: Receives Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jennifer Rumpel, MD

University of Arkansas for Medical Sciences

Phone: 501-364-2980

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place