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Hypoxemia in Maintenance Hemodialysis Patients

NCT03045796 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2017-05-11

No results posted yet for this study

Summary

Previous research has shown that many patients with kidney failure undergoing chronic hemodialysis (HD) have a very low venous oxygen concentration, which may further decrease during dialysis treatments. This may be due to a variety of factors including anemia, compromised pulmonary function, and chronic fluid volume overload. Previous studies have shown that low venous oxygen concentrations may increase the risk of cardiovascular events, cognitive deficits, and mortality in HD patients.

The purpose of this study is to identify patients with hypoxemia during HD treatments and characterize the extent of and implications of their hypoxemia. Specifically, the investigators aim to examine the relationship between central venous oxygen concentration and hemodynamic changes during dialysis treatment. The investigators will evaluate the relationship between cardiac output as measured by the Task Force Monitor and central venous oxygen saturation as measured by the Crit-Line Monitor and Wrist0x2 in HD patient. Data from this study will provide insight into potential mechanisms responsible for side effects associated with dialysis treatment, such as drops in blood pressure and cognitive dysfunction.

Conditions

  • Oxygen Saturation and the Relationship to Other Cardiac Variables
  • Maintenance Hemodialysis
  • Kidney Failure, Chronic

Interventions

DEVICE

Oxygen Saturation measured by WristOx

Patients will be hooked up to finger cuffs as well as ECGs to monitor oxygen saturations in different part of the body.

Sponsors & Collaborators

  • Renal Research Institute

    collaborator OTHER

  • University of Illinois at Urbana-Champaign

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-01
Primary Completion
2018-01-31
Completion
2018-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03045796 on ClinicalTrials.gov