Relation Between Cachexia, Diabetes and periNeural Invasion in PANcreatic Cancer- Biomarkers Substudy
NCT03042442 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 114
Last updated 2019-03-19
Summary
The purpose of this study is to determine the interrelationship between cachexia, neural invasion and diabetes in patients with pancreatic cancer. Thus the investigators propose to identify the protein expression levels of Activin and Midkine in plasma of patients with different stages of pancreatic adenocarcinoma compared with healthy patients and to evaluate the possible correlation with diabetes, tumor size and tumor stage.
Conditions
- Pancreatic Cancer, Adult
- Cachexia
- Pain
- Diabetes Mellitus
Interventions
- DIAGNOSTIC_TEST
-
Point-of care biomarkers
Point-of care biomarkers(Activin,Midkine) assessed by WB and IHC
- OTHER
-
Clinical, venous blood samples, pancreatic tissue
Clinical evaluation, venous blood samples and pancreatic tissue needed for determining point-of-care biomarkers.
- OTHER
-
Follow-up
Participants will be assessed (by telephone) over a period of 2 years
Sponsors & Collaborators
-
Iuliu Hatieganu University of Medicine and Pharmacy
lead OTHER
Principal Investigators
-
Livia Petrusel, MD, PhD · Iuliu Hatieganu University of Medicine
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-01
- Primary Completion
- 2018-06-30
- Completion
- 2018-09-30
Countries
- Romania
Study Locations
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