Relation Between Cachexia, Diabetes and periNeural Invasion in PANcreatic Cancer- Biomarkers Substudy

NCT03042442 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 114

Last updated 2019-03-19

No results posted yet for this study

Summary

The purpose of this study is to determine the interrelationship between cachexia, neural invasion and diabetes in patients with pancreatic cancer. Thus the investigators propose to identify the protein expression levels of Activin and Midkine in plasma of patients with different stages of pancreatic adenocarcinoma compared with healthy patients and to evaluate the possible correlation with diabetes, tumor size and tumor stage.

Conditions

Interventions

DIAGNOSTIC_TEST

Point-of care biomarkers

Point-of care biomarkers(Activin,Midkine) assessed by WB and IHC

OTHER

Clinical, venous blood samples, pancreatic tissue

Clinical evaluation, venous blood samples and pancreatic tissue needed for determining point-of-care biomarkers.

OTHER

Follow-up

Participants will be assessed (by telephone) over a period of 2 years

Sponsors & Collaborators

  • Iuliu Hatieganu University of Medicine and Pharmacy

    lead OTHER

Principal Investigators

  • Livia Petrusel, MD, PhD · Iuliu Hatieganu University of Medicine

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2018-06-30
Completion
2018-09-30

Countries

  • Romania

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03042442 on ClinicalTrials.gov