MedTrace Logo

Ultra Protective Ventilation During Venoarterial Extracorporeal Membrane Oxygenation (UPV-ECMO)

NCT03041428 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2021-04-01

No results posted yet for this study

Summary

Mechanical ventilation, in spite of being a life-saving technique, can also induce lung injury (VILI) mediated by an inflammatory response, thus having a profound impact in the course of critically ill patients. Ventilatory strategies aimed to minimize this VILI have reduced mortality rates. Patients suffering cardiogenic pulmonary edema may need venoarterial extracorporeal oxygenation, at the same time they are being mechanically ventilated. The objective of this study is to analyze changes induced by the use of utraprotective ventilatory strategies in the inflammatory lung response of these patients and their impact on outcomes.

Conditions

  • Cardiogenic Pulmonary Edema
  • Ventilator-Induced Lung Injury
  • Extracorporeal Circulation; Complications

Interventions

DEVICE

Ultraprotective ventilation

Adjusting ventilator parameters for 3 ml/kg of tidal volume in order to achieve the ultra protective strategy

Sponsors & Collaborators

  • Fundación para la Investigación Biosanitaria del Principado de Asturias

    lead OTHER

Principal Investigators

  • Guillermo M Albaiceta · HUCA-FINBA, Universidad de Oviedo

Study Design

Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-02-01
Primary Completion
2019-12-31
Completion
2021-03-01

Countries

  • Spain

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03041428 on ClinicalTrials.gov