Adaptive Immune Responses and Repertoire in Influenza Vaccination and Infection (SLVP031)
NCT03028987 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2017-09-12
Summary
The purpose of this study is provide a better understanding of the adaptive immune response to the licensed flu vaccines. The investigators hope the information learned from this study will help identify and describe important factors of influenza immunity especially of or specific proteins associated with the T-cell immune response.
Conditions
Interventions
- BIOLOGICAL
-
Fluzone®
Fluzone® Quadrivalent (IIV4; inactivated influenza virus vaccine)
- BIOLOGICAL
-
FluMist®
FluMist® Intranasal Spray (quadrivalent, live, attenuated influenza vaccine)
Sponsors & Collaborators
-
National Institute of Allergy and Infectious Diseases (NIAID)
collaborator NIH - lead OTHER
Principal Investigators
-
Cornelia Dekker, MD · Stanford University
-
Mark Davis, PhD · Stanford University
-
K. Christopher Garcia, PhD · Stanford University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 49 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-11-19
- Primary Completion
- 2015-11-18
- Completion
- 2015-11-18
Countries
- United States
Study Locations
More Related Trials
-
B-cell Immunity to Influenza (SLVP017) - Years 2 (2010) & 3 (2011)
NCT03020498 ·Status: COMPLETED ·Phase: PHASE4
-
Plasmablast Trafficking and Antibody Response in Influenza Vaccination (SLVP021 2011-2014)
NCT02141581 ·Status: COMPLETED ·Phase: PHASE4
-
The Role of CD4+ Memory Phenotype, Memory, and Effector T Cells in Vaccination and Infection
NCT03453801 ·Status: COMPLETED ·Phase: PHASE1
-
Response to Inactivated Influenza Vaccine in Lymph Tissue and Blood
NCT03898973 ·Status: WITHDRAWN ·Phase: PHASE4
-
Response to Live Attenuated Influenza Vaccine in Tonsillar Tissues and Blood
NCT03884296 ·Status: WITHDRAWN ·Phase: PHASE4
-
Live Attenuated Influenza Vaccine (LAIV) Versus Trivalent Inactivated Influenza Vaccine in Healthy Adults 18-49 Years
NCT03101462 ·Status: COMPLETED ·Phase: PHASE4
-
B-cell Immunity to Influenza (SLVP017)- Year 5, 2013
NCT03020537 ·Status: COMPLETED ·Phase: PHASE4
-
The Human Mucosal Immune Responses to Influenza Virus (SLVP026)
NCT03023553 ·Status: COMPLETED ·Phase: PHASE4
-
T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) - Year 1, 2009
NCT01987349 ·Status: COMPLETED ·Phase: PHASE4
-
Influenza Immunity Against Pandemic Respiratory Virus
NCT00138281 ·Status: COMPLETED ·Phase: PHASE4
-
T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 2, 2010
NCT03022396 ·Status: COMPLETED ·Phase: PHASE4
-
T and B Cell Response to Avian Flu Vaccine
NCT00337896 ·Status: COMPLETED
-
T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 5, 2013
NCT03023176 ·Status: COMPLETED ·Phase: PHASE4
-
T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 4, 2012
NCT03022435 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase I Safety and Immunogenicity Study of Mix and Match of Licensed Flu Vaccine and Flumist
NCT00231907 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Immune Responses in Healthy Adults Receiving Live Influenza Virus Vaccines
NCT01674205 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Three Licensed Influenza Vaccines
NCT03068949 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Immunogenicity of Quadrivalent Live Attenuated Influenza Vaccine (LAIV) in Children
NCT01091246 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study in Young Adults to Examine the Kinetics of Changes in the B-cell Repertoire Following TIV Immunization
NCT02987374 ·Status: COMPLETED ·Phase: PHASE4
-
Influenza Vaccine in Pediatric Transplant Subjects
NCT00133510 ·Status: COMPLETED ·Phase: PHASE4
-
Immunologic Response to Influenza Vaccination in Children and Adolescents
NCT03614975 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Immunogenicity of Quadrivalent LAIV in Adults 18 to 49 Years of Age
NCT00860067 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Comparison of Inactivated and Live, Attenuated Influenza Vaccine in Children 5-9 Years of Age-Year 3 Amendment
NCT00138385 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of Attenuated Versus Inactivated Flu Vaccine in Twin Sets
NCT03898986 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 2 Study to Evaluate Immune Responses of FluMist®
NCT00461981 ·Status: COMPLETED ·Phase: PHASE2