A Clinical Trial With Apatinib for Subjects With Refractory Malignant Ascites
NCT03020979 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2017-05-31
Summary
Malignant ascites is a severe complication of many types of human cancer. Animal and clinical analyses have shown that angiogenesis plays a critical role in the formation of malignant ascites. Therefore, drugs such as apatinib that target angiogenesis may control the development of malignant ascites. The study is to evaluate the efficacy and safety of apatinib in patients with refractory malignant ascites.
Conditions
- Malignant Ascites
- Apatinib
Interventions
- DRUG
-
Apatinib
Patients will take 500mg apatinib daily orally.
Sponsors & Collaborators
-
The First Affiliated Hospital of Bengbu Medical University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-31
- Primary Completion
- 2018-12-31
- Completion
- 2019-12-31
Countries
- China
Study Locations
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