Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve Amyloidosis
NCT03019029 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2026-03-16
Summary
The primary aim of this study will be to examine the diagnostic utility of 18-F Florbetapir PET/MR (Positron Emission Tomography/Magnetic Resonance) in imaging patients with pathologically-confirmed systemic amyloidosis involving the peripheral nerves and compare these results to non-amyloid diseased controls.
Conditions
- Amyloidosis
Interventions
- OTHER
-
18-F Florbetapir PET/MR scan
18-F Florbetapir PET/MR scan, PET/MR on a GE SIGNA PET/MR scanner
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Stephen M. Broski, M.D. · Mayo Clinic
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-03-13
- Primary Completion
- 2022-03-24
- Completion
- 2022-03-24
Countries
- United States
Study Locations
More Related Trials
-
Tau PET Outcomes With Anti-amyloid Immunotherapies
NCT06723015 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Amyloid-beta PET Imaging With 18F-92 in Alzheimer's Disease
NCT04926272 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers
NCT01009359 ·Status: COMPLETED ·Phase: PHASE1
-
Impact of FBB PET Amyloid Imaging in Change of Diagnosis in Patients With AD
NCT02681172 ·Status: COMPLETED ·Phase: PHASE4
-
F 18 T807 Tau PET Imaging in Familial Amyotrophic Lateral Sclerosis
NCT02414230 ·Status: COMPLETED
-
Positron Emission Tomography (PET) Imaging of Brain Amyloid Compared to Post-Mortem Levels
NCT01165554 ·Status: COMPLETED ·Phase: PHASE3
-
Neuroimaging Study
NCT03618186 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral Beta-Amyloid When Compared With Postmortem Histopathology
NCT01886820 ·Status: UNKNOWN ·Phase: PHASE3
-
PET/MRI in the Diagnosis of Chronic Pain
NCT03556137 ·Status: UNKNOWN ·Phase: PHASE1
-
Positron Emission Tomography of Amyloid in Alzheimer's Disease
NCT00205621 ·Status: SUSPENDED ·Phase: PHASE1
-
Radioimmunoimaging of Light Chain (AL) Amyloidosis
NCT01815086 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Imaging in Demyelinating Diseases
NCT05805839 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Evaluation of [18F]MNI-952 as a Potential PET Radioligand for Imaging Tau Protein in the Brain
NCT03080051 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Molecular PET Imaging and Plasma Biomarkers in Alzheimer´s Disease and Other Neurodegenerative Diseases
NCT06731842 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Cerebral Amyloid Imaging Using Florbetapir (AV-45)
NCT02813434 ·Status: UNKNOWN ·Phase: PHASE3
-
Radioimmunoimaging of AL Amyloidosis
NCT01409148 ·Status: COMPLETED ·Phase: PHASE1
-
Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
NCT02740634 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects
NCT04141150 ·Status: UNKNOWN ·Phase: PHASE2
-
F 18 T807 Tau PET Imaging of Alzheimer's Disease
NCT02414347 ·Status: RECRUITING
-
Safety and Efficacy of Positron Emission Tomography (PET) Imaging With MNI-558
NCT01217021 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pan-Amyloid PET/CT in Various Amyloid-Related Disease
NCT07130565 ·Status: RECRUITING
-
Radioimmunoimaging of AL Amyloidosis
NCT00807872 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Evaluation of [18F]MK-6240 PET as an Imaging Marker for Tau Protein
NCT03071224 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Beta-Amyloid Imaging With [18F]NAV4694 PET in Predicting Progression to AD in Subjects MCI
NCT01812213 ·Status: TERMINATED ·Phase: PHASE2
-
[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD
NCT06120049 ·Status: RECRUITING ·Phase: PHASE2/PHASE3