Association Study Between CYP1A2 Gene Polymorphisms and Metabolism of Theophylline
NCT03015090 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 110
Last updated 2022-03-17
Summary
The aim of this study is to determine whether common CYP1A2 gene polymorphisms effect metabolism of theophylline in Han and Uygur Patients with chronic obstructive pulmonary disease patients.
Conditions
Interventions
- DRUG
-
Theophylline
After oral theophylline 200mg per day for one week, blood sample will be collected for determining plasma concentrations of theophylline and it's metabolites and the genotypes of CYP1A2
Sponsors & Collaborators
-
Southern Medical University, China
collaborator OTHER -
XiaoGuang Zou
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-01
- Primary Completion
- 2017-06-01
- Completion
- 2017-06-01
Countries
- China
Study Locations
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