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Dual AntiPlatelet Therapies for Prevention of Periinterventional Embolic Events in TAVI

NCT03001960 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2016-12-28

No results posted yet for this study

Summary

TAVI is increasingly adopted as standard treatment for many subgroups of patients with aortic stenosis. However, due to a lack of data there is yet no TAVI-specific guidance regarding the optimum periinterventional drug regimen.

The study evaluates the effect of dual antiplatelet pretreatment on periinterventional embolic cerebral lesions and bleeding complications in patients undergoing transfemoral aortic valve implantation (TF-TAVI).

Conditions

  • Aortic Valve Stenosis
  • Transcatheter Aortic Valve Replacement
  • Intracranial Embolism

Interventions

DRUG

Preloading before TAVI

Preloading with Aspirin and Clopidogrel before TAVI

DRUG

Postloading after TAVI

Postloading with Aspirin and Clopidogrel after TAVI

Sponsors & Collaborators

  • Prof. Dr. Jochen Fiebach, Center for Stroke Research Berlin (CSB), Charité - Universitaetsmedizin Berlin

    collaborator UNKNOWN

  • Charite University, Berlin, Germany

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-31
Primary Completion
2018-03-31
Completion
2018-04-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03001960 on ClinicalTrials.gov