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Role of Biomarkers in Patients Undergoing Dialysis Treatment

NCT02962635 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2021-08-10

No results posted yet for this study

Summary

A precise volume status assessment is critical to improve outcome of patients on dialysis. Yet, accurate assessment of fluid status remains a challenge. Currently, this is performed by clinical evaluation and regular weight measurements before and after dialysis, which is not always accurate. Moreover, bioimpedance technology is used in some centers for quantitative assessment of total body water. This approach has been validated for the assessment of volume status in dialysis patients, but requires the acquisition of specific tools and is time consuming. So far, no biomarker has been validated to quantify volume status in dialysis patients. Application of biomarkers might contribute to a better dialysis prescription and therefore to outcome improvement in dialysis. The investigators aim to investigate the role of a novel biomarkers (sCD146) to assess volume status in dialysis patients

Conditions

  • Volemia in Dialysis Patients

Interventions

DEVICE

bioelectrical impedance measurement and biomarker measurement

Measuring volume status with bioelectrical impedance measurement and comparing with biomarker level

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV

  • University of Zurich

    lead OTHER

Principal Investigators

  • Stephan Segerer, MD · University Hospital Zürich, Zürich, Switzerland

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-10-31
Primary Completion
2019-01-31
Completion
2019-01-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02962635 on ClinicalTrials.gov