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Blood Transfusions in Coronary Artery Bypass Surgery

NCT02953951 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 95

Last updated 2016-11-03

No results posted yet for this study

Summary

The hemolytic product free-hemoglobin (fHb) reduces nitric oxide (NO) bioavailability. The present study aims to establish whether transfusions of stored allogenic blood or intraoperative autologous salvaged blood result in increased circulating fHb levels and NO consumption with effects on arterial NO-dependent blood flow measured in isolated left mammary artery rings and by peripheral artery tonometry in patients undergoing CABG surgery.

Conditions

  • Excessive Amount of Blood / Fluid Transfusion

Interventions

OTHER

blood transfusion

blood transfusion different sources

Sponsors & Collaborators

  • Universita di Verona

    lead OTHER

Principal Investigators

  • Alessio Rungatscher, MD, PhD · Universita di Verona

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2014-05-31
Completion
2015-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02953951 on ClinicalTrials.gov