NeoVax Plus Ipilimumab in Renal Cell Carcinoma
NCT02950766 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2026-02-03
Summary
This research study is evaluating a new type of Kidney Cancer vaccine called "Personalized NeoAntigen Cancer Vaccine"as a possible treatment for Kidney Cancer.
The following intervention will be involved in this study:
* Personalized Neoantigen Vaccine
* Poly-ICLC (Hiltonol)
* Ipilimumab
Conditions
Interventions
- DRUG
-
NeoVax
combination of Neoantigen peptides and poly-ICLC
- DRUG
-
local administration of ipilimumab
Sponsors & Collaborators
- collaborator INDUSTRY
-
Oncovir, Inc.
collaborator INDUSTRY -
Patrick Ott, MD, PhD
lead OTHER
Principal Investigators
-
Patrick Ott, MD · Dana-Farber Cancer Institute
-
Toni Choueiri, MD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-03
- Primary Completion
- 2027-12-31
- Completion
- 2030-05-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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