Influence of the Different Ways of Appendix Stump Closure on Patient Outcome in Laparoscopic Appendectomy

Summary

During laparoscopic appendectomy, the base of the appendix is usually secured by an endoloop ligature or the stapler. Non-absorbable plastic hem-o-lok clip was shown as an alternative technique with which laparoscopic appendectomy was done faster and cheaper than the standard techniques. However, biocompatibility of different materials udes in securing the base of appendix is different. It was observed that stapler's clips made by titanium caused the mildest inflammatory reaction and creation of adhesions. Disadvantages of stapler's are their high price.

Titanium clips made for the use in laparoscopic appendectomy are safe and effective option in securing the appendicular stump in laparoscopic appendectomy. They have potential advantages over stapler, because they have the same bio compatibility, and their price is lower.

Conditions

• Appendicitis

Interventions

PROCEDURE

E group

The securing the base of appendix by endoloop.

PROCEDURE

S group

The securing the base of appendix by Stapler.

PROCEDURE

H group

The securing the base of appendix by Hem-o-lok clip.

PROCEDURE

DS group

The securing the base of appendix by DS clip.

DEVICE

Endoloop

DEVICE

Stapler

DEVICE

Hem-o-lok clip

DEVICE

DS clip

Sponsors & Collaborators

• University Clinical Center Tuzla

  lead OTHER

Principal Investigators

• Enver Zerem, MD, PhD · University Clinical Center Tuzla

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-10-02

Primary Completion

2016-12-30

Completion

2017-01-30

Countries

• Bosnia and Herzegovina

Study Locations