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Hunger and Satiety in Anorexia Nervosa

NCT02932046 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 47

Last updated 2016-10-13

No results posted yet for this study

Summary

Anorexia means loss of appetite. But there is disagreement about whether the appetite is changed by the disease anorexia nervosa (AN). Appetite is a subjective essential sense, which is regulated in a complex ensemble between brain, stomach - intestinal system and hormones. As a direct result of malnutrition, there are many somatic complications caused by the disease AN. Several of these complications may in itself affect hunger- and satiety perception. An example of this is delayed gastric emptying. Furthermore, changes in the hormone systems affects the biological "reward system" in the brain, which plays an important role in appetite regulation. There is clearly need for research that could lead to better treatments for AN. Hunger- and satiety perception has only been studied in a few small cross-sectional studies with no clear conclusion.

The purpose of the study is to determine whether a visual analog scale measurement can detect changes in hunger- and satiety perception in a least 30 patients admitted to nutrition for life-threatening severe anorexia nervosa. It may lead to the first step in the development of a simple and inexpensive instrument which may prove to be useful in measuring the impact of new and ongoing treatments of the disease.

Conditions

  • Anorexia Nervosa
  • Appetite Disorders

Interventions

DIETARY_SUPPLEMENT

Standardized noon meal

The meal is "treatment as usual" in the specialized somatic stabilization ward for patients with severe anorexia nervosa.

Sponsors & Collaborators

  • Odense University Hospital

    lead OTHER

Principal Investigators

  • René Stoving, PhD · Odense UH, Denmark

Eligibility

Min Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02932046 on ClinicalTrials.gov