MedTrace Logo

Single Cell Genomics of Psoriatic Skin

NCT02929745 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2021-09-23

No results posted yet for this study

Summary

The purpose of this study is to understand how genetics play a role in psoriasis. Specifically, a genetic allele HLA-Cw6 is known to be associated with psoriasis, and this study aims to find out how it affects genetic and protein expression in patients with psoriasis, compared to healthy people, at a single-cell level using a novel flow cytometry and RNA-sequencing protocol.

Conditions

Interventions

PROCEDURE

Skin biopsy

Four 4-5 mm punch biopsies of the skin

PROCEDURE

Blood draw

Blood will be drawn to test for HLA-cw6 status

Sponsors & Collaborators

Principal Investigators

  • Wilson Liao, MD · University of California, San Francisco

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-07-01
Primary Completion
2020-12-09
Completion
2020-12-09

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02929745 on ClinicalTrials.gov