Investigation of Mechanisms for Transmission of Impaired Glucose Metabolism in Infants Exposed to Diabetes in Utero
NCT02926079 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18
Last updated 2022-09-27
Summary
This proposed study; Investigation of mechanisms for transmission of impaired glucose metabolism in infants exposed to diabetes in utero, will test the overarching hypothesis that impaired maternal substrate oxidation (metabolic inflexibility) and placental lipotoxicity are characteristics of diabetic pregnancies and in utero development within these conditions programs a metabolically inflexible phenotype in the offspring.
Conditions
- Pregnancy
- Gestational Diabetes Mellitus
Sponsors & Collaborators
-
University of Colorado, Denver
collaborator OTHER -
Pennington Biomedical Research Center
lead OTHER
Principal Investigators
-
Leanne M Redman, PhD · Pennington Biomedical Research Center
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-05-23
- Primary Completion
- 2018-11-08
- Completion
- 2019-01-08
Countries
- United States
Study Locations
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