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Functional and Anatomical MRI of the Spinal Cord and Peri-spinal Tissues

NCT02925364 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 17

Last updated 2023-06-22

No results posted yet for this study

Summary

The current study is an amendment to a previously approved blinded randomized controlled trial (NCT02697812) which examines the rate at which the sternal retraction maneuver is performed during cardiac surgery (standard over 30 seconds versus. gradual over 15 minutes) and examines the incidence of chronic post-sternotomy pain 6 months following surgery.

Patients enrolled in the parent study will be identified at the 6 month follow-up and recruited in terms of whether they report chest pain. A total of 30 participants will be recruited (15 with and 15 with no pain) to undergo a single MRI session in which functional MRI will be done on the brain stem and spinal cord and anatomical MRI images will be collected for specific chest and neck structures. This will indicate whether there are long-term differences in pain processing and/or physical damage to neck and chest structures in those with and without chronic pain 6 months following coronary artery bypass graft surgery. All functional and anatomical MRI images will be reviewed and interpreted with study personnel blinded to whether the patient is reporting pain or no pain at their 6 month follow-up interview.

Conditions

  • Chronic Pain
  • Other Functional Disturbances Following Cardiac Surgery

Interventions

RADIATION

magnetic resonance imaging (MRI)

all participants will undergo a functional MRI and an anatomical MRI in a single session

Sponsors & Collaborators

  • Dr. Tarit Saha

    lead OTHER

Principal Investigators

  • Tarit Saha, MD, FRCPC · Queen's University

  • Patrick Stroman, PhD · Queen's University-Cenre for Neuroscience Studies

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2020-01-31
Completion
2020-01-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02925364 on ClinicalTrials.gov