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Multicenter Validation of the AVICH Score

NCT02920645 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2016-09-30

No results posted yet for this study

Summary

The primary objective of this multicenter study is to validate the AVICH score in terms of patient outcome prediction in AVM patients with associated ICH.

Secondary objectives are the impact of pretreatment of the AVICH score. Patients outcome is measured using the modified Rankin Scale (mRS) and are grouped in favorable (mRS score, 0-2) and unfavourable (mRS score, 3-6) outcome at last follow-up (LFU). The following parameters, which are part of the AVICH score, will be compared between the 2 groups: ICH score including age, Glasgow Coma Scale (GCS) score, haemorrhage volume, presence of intraventricular hemorrhage (IVH), and localization of the ICH. Spetzler-Martin grade including AVM size, eloquent location, and venous drainage, as well as the Lawton-Young grade, including age, presence of ruptured AVM, and the nidus structure. In addition pre-/postruptured treatment modalities, including embolization, radiotherapy, surgery or no treatment will be analysed. Outcome (mRS) at 3 months, at 1 year, and at LFU will be compared.

Multicentre validation study

Key inclusion criteria:

* All patients with ICH associated AVMs and a modified Rankin Scale \<2 (so 0-1) before hemorrhage
* Pretreatment (embolization, radiosurgery, surgery) before ICH is not an exclusion criteria.

Key exclusion criteria:

* incomplete data set
* AVM Patients with only subarachnoid hemorrhage (SAH) or IVH and no ICH

Conditions

  • Intracerebral Hemorrhage
  • Arterio-venous Malformation

Interventions

OTHER

AVM-related ICH

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Jan-Karl Burkhardt, MD · Department of Neurosurgery, University Hospital Zurich, University of Zurich

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2016-12-31
Completion
2016-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02920645 on ClinicalTrials.gov