MedTrace Logo

Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation

NCT02911129 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2025-02-27

No results posted yet for this study

Summary

Background:

After a stroke, the balance between the two halves of the brain can be lost. This may cause people to lose the ability to perceive a side of space. This is called neglect. Having people wear prism glasses (called PA) can reduce neglect symptoms. Researchers want to find out more about how PA, and whether it restores the balance in the brain.

Objective:

To learn how prism adaption temporarily changes vision and connections in the brain.

Eligibility:

People ages 18 75 with brain damage of the right side of the brain from a stroke or other cause, leading to neglect.

Healthy volunteers ages 18 75.

Design:

Participants will have 1 3 visits.

Participants will be screened with a neurological exam. They may also have:

Tests of thinking and vision

Tests to see which eye and hand they prefer

A pregnancy test

All participants will:

Answer questions about their personality, style of thinking, and beliefs.

Do simple tasks on paper or computer

Have magnetic resonance imaging. They will lie on a table that can slide in and out of a cylinder in a strong magnetic field. Participants will lie still or do computer tasks in the scanner.

Participants may also have:

Transcranial magnetic stimulation. A brief electrical current passes through a wire coil on the scalp. This creates a magnetic pulse that affects brain activity. Participants may be asked to tense certain muscles or perform simple actions or tasks.

PA. They will sit in front of a board and point to a dot on it while they wear prism glasses that shift vision to the left or right....

Conditions

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    lead NIH

Principal Investigators

  • Eric M Wassermann, M.D. · National Institute of Neurological Disorders and Stroke (NINDS)

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-04
Primary Completion
2018-12-21
Completion
2025-02-24

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02911129 on ClinicalTrials.gov