MedTrace Logo

Study of Gut Microbiota in Primary Immune Deficiency, Possibly Associated With Inflammatory Bowel Disease

NCT02909244 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 51

Last updated 2017-08-25

No results posted yet for this study

Summary

Some Primary Immune Deficiencies can be associated with an inflammatory bowel disease, mimicking Crohn disease : the Chronic Granulomatous Disease (CGD), the XIAP deficiency, and the TTC7A deficiency.

This inflammatory bowel disease is frequent but inconstant, raising questions about other factors contributing to the disease. The aim of our study is to analyze, describe and compare the gut microbiota of patients with those primary immune deficiency, with or without intestinal disease.

The investigators can expect, in the long term, to compare on a same patient, the gut microbiota evolution, and to assess the role of gut microbiota modifications on the onset of an inflammatory bowel disease.

Conditions

  • Primary Immune Deficiencies

Interventions

BIOLOGICAL

Biological sampling

Biological sampling

Sponsors & Collaborators

  • Saint Antoine University Hospital

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    collaborator OTHER

  • Imagine Institute

    lead OTHER

Principal Investigators

  • Sylvain Latour · Imagine Institute

  • Alain Fischer · Imagine Institute

  • Harry Sokol · Saint-Antoine Hospital

  • Olivier Join-Lambert · Necker - Enfants malades Hospital

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-02-28
Primary Completion
2017-02-28
Completion
2017-02-28

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02909244 on ClinicalTrials.gov