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Effect of Product Related Factors on Platelet Concentrate Transfusion Response in Patients With Hematologic Malignacies

NCT02885038 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1101

Last updated 2017-10-02

No results posted yet for this study

Summary

Platelet concentrates (PCs) characteristics, such as storage duration, ABO compatibility, dose and source, may have an impact on transfusion responses and outcomes. Because of the relative scarcity of PCs the selection of a specific PC for issue to the patient remains a challenging process. Regulatory agencies do not fully address these characteristics in their recommendations for prophylactic transfusions.

The aim of the study was to analyse the effect of product-related factors in a real life setting, in order to determine which ones are the most relevant when selecting PCs for patients in prophylactic conditions. Two different endpoints are studied: the corrected count increment and the platelet transfusion time intervals.

Conditions

Interventions

OTHER

Platelet concentrate transfusion

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Besancon

    collaborator OTHER

  • Etablissement Français du Sang

    lead OTHER

Principal Investigators

  • Laurent BARDIAUX, MD · Etablissement Français du Sang

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2016-03-31
Completion
2016-03-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02885038 on ClinicalTrials.gov