Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects
NCT02855073 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2018-12-17
Summary
The purpose of this study is to evaluate the effectiveness of ReJoinTM for the Knee Osteoarthritis patients with Cartilage Defects comparing to Sodium Hyaluronate Injection.
Conditions
- Defect of Articular Cartilage
- Knee Osteoarthritis
Interventions
- BIOLOGICAL
-
ReJoinTM
adipose derived mesenchymal progeinitor cells
- DRUG
-
Sodium Hyaluronate
Sodium Hyaluronate Injection
Sponsors & Collaborators
-
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
collaborator OTHER -
Shanghai AbelZeta Ltd.
lead INDUSTRY
Principal Investigators
-
You Wang · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-07-31
- Primary Completion
- 2019-12-31
- Completion
- 2019-12-31
Countries
- China
Study Locations
More Related Trials
-
Clinical Trial to Evaluate Efficacy and Safety of JOINTSTEM in Patients With Degenerative Arthritis
NCT02658344 ·Status: COMPLETED ·Phase: PHASE2
-
Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis
NCT04208646 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis
NCT04368806 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Autologous Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis
NCT03788265 ·Status: UNKNOWN ·Phase: NA
-
Investigator Initiated Trial to Evaluate Cartilage Regeneration by Arthroscopy After JOINTSTEM Administration
NCT04821102 ·Status: UNKNOWN ·Phase: NA
-
Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment
NCT02848027 ·Status: COMPLETED ·Phase: PHASE3
-
Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study
NCT03898388 ·Status: TERMINATED ·Phase: NA
-
A Phase 3 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis
NCT03990805 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Knee Osteoarthritis (KOA) by Injection of Autologous Adipose-derived Vascular Matrix Components (SVF) Into Joint Cavity
NCT06109220 ·Status: UNKNOWN ·Phase: NA
-
PRP vs HA Intra-articular Knee Injections for Cartilage Defects
NCT02012530 ·Status: UNKNOWN ·Phase: NA
-
A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis
NCT02838069 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee
NCT03101163 ·Status: COMPLETED ·Phase: PHASE2
-
Follow-up Study for Participants of Jointstem Phase 3 Clinical Trial
NCT04427930 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis
NCT04130100 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Treatment of Knee Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells
NCT02123368 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of PRP Joint Cavity Combined with Acupoint Injection on Osteoarthritis of Knee Joint
NCT06688682 ·Status: COMPLETED ·Phase: NA
-
Cellular Matrix Device for the Treatment of Mild to Moderate Knee Osteoarthritis
NCT03328728 ·Status: UNKNOWN ·Phase: NA
-
Long-term Evaluation of Outcomes of Patients Undergoing Autologous Bone Marrow Concentrate Infiltration vs. Hyaluronic Acid
NCT06164899 ·Status: COMPLETED
-
Mesenchymal Stem Cells Enhanced With PRP Versus PRP In OA Knee
NCT01985633 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
The Comparison of Efficacy and Safety of the Mesenchymal Stem Cells From Adipose and Hyaluronic Acid
NCT03357575 ·Status: UNKNOWN ·Phase: NA
-
Intraosseous With Intra-articular Injection of Platelet Rich Plasma in Treatment of Knee Osteoarthritis
NCT03329235 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells in Subjects With Osteoarthritis
NCT03602872 ·Status: WITHDRAWN ·Phase: PHASE1
-
Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction
NCT01088191 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury
NCT03955497 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Effectiveness of Autologous Platelet-rich Plasma on Knee Cartilage Injury
NCT03024801 ·Status: COMPLETED ·Phase: NA