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Muscular Force Generation in Microgravity

NCT02850328 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2017-08-18

No results posted yet for this study

Summary

The aim of this study is to evaluate the applicability of high-load resistance training as a countermeasure for long term space flights, the current project has two scientific goals.

The main objective is to perform a deeper examination of muscle function and MVC in weightlessness (parabolic flight).

The secondary objective is to gather further insight into the underlying mechanisms and structures based on investigations targeting the neuromuscular and musculotendinous systems and their interaction.

Conditions

  • Maximum Voluntary Contraction

Interventions

OTHER

examination of muscle function and MVC in weightlessness

MVC tested during three different tasks: (1) leg press, (2) plantarflexion and (3) grip strength. parameters of muscle function that can be easily implemented in parabolic flight: * Rate of force development * Electromyographic activity * Ultrasound measure: fascicle length and pennation angle of the gastrocnemius medialis muscle * Superimposed twitch torque (M-waves at rest and V-waves in MVC conditions) * Maximum voluntary activation capacity (%VA): %VA = (1-\[torque superimposed twitch/torque resting twitch\])\*100%.

Sponsors & Collaborators

  • Novespace

    collaborator INDUSTRY

  • University Hospital, Caen

    lead OTHER

Principal Investigators

  • Pierre DP Denise, PhD · UMR 1075 UFR de Médecine Caen

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-09-30
Primary Completion
2017-09-30
Completion
2017-10-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02850328 on ClinicalTrials.gov