Difference of Gastric Microbiota in the Process of Correa's Model.
NCT02833363 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2016-10-26
Summary
Helicobater pylori plays an important role in the development of gastric cancer. Eradication therapy can reducing the morbidity of gastric cancer, but can't totally prevent it especially when atrophy and more serious precancerous lesions already happened. Prior studies found the gastric bacterial difference among gastritis, intestinal metaplasia and gastric cancer. However, they didn't reach an agreement. Correa's model is widely accepted in the development of gastric cancer. The pathological change makes a more suitable environment for bacteria to overgrowth. This study are designed to analyze the gastric microbial difference of non-atrophic gastritis, atrophic gastritis, intestinal metaplasia, intraepithelial neoplasia and gastric cancer.
Conditions
- Gastric Microbiota
- Non-atrophic Gastritis
- Atrophic Gastritis
- Intestinal Metaplasia
- Intraepithelial Neoplasia
- Gastric Cancer
- Helicobacter Pylori
Sponsors & Collaborators
-
Shandong University
lead OTHER
Principal Investigators
-
Yanqing Li, MD,PHD · Qilu Hospital of Shandong University
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-07-31
- Primary Completion
- 2016-12-31
- Completion
- 2017-02-28
Countries
- China
Study Locations
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