Intraoperative Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods.
NCT02830516 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24
Last updated 2018-01-08
Summary
Classically lung elastance and transpulmonary pressure are measured from the difference in tidal variations of airway pressure subtracted by tidal variations i esophagus pressure divided by the tidal volume. This requires the presence of a esophageal balloon catheter which is cumbersome and costly. In this study values obtained as described above are compared to values obtained with a new method in which a stepwise increase in positive endexpiratory pressure (PEEP) is performed with a size which corresponds to the tidal volume which the patient is ventilated with. These measurements are performed in anesthetized patients prior to major surgery.
Conditions
- Anesthesia
Interventions
- OTHER
-
Measurement of lung elastance by two methods
Measurement of tidal variations in esophageal pressure followed in the same patient by performing a PEEP-step while simultaneously measuring the change in lung volume
Sponsors & Collaborators
-
Stefan Lundin
lead OTHER
Principal Investigators
-
Stefan Lundin, Professor · Sahlgrenska University Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-06-30
- Primary Completion
- 2016-12-31
- Completion
- 2016-12-31
Countries
- Sweden
Study Locations
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