MedTrace Logo

Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes

NCT02819570 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2016-12-29

No results posted yet for this study

Summary

The objective of the study is to compare a new antibiotic protocol with the current prophylactic treatment in routine use and to evaluate obstetric and neonatal outcome: preterm labor, chorioamnionitis and early onset sepsis

Conditions

  • Premature Rupture of Membrane

Interventions

DRUG

P.O moxypen 500 mgx3/d for 5 days

DRUG

I.V cefuroxime 750 mg*3/d for 2 days

DRUG

I.V ampicillin 2 gram x4/d for 2 days

DRUG

P.O cefuroxime 500 mgx2/d for 5 days

DRUG

P.O roxithromycin 150 mg*2/d for 7 days

Sponsors & Collaborators

  • Western Galilee Hospital-Nahariya

    lead OTHER_GOV

Principal Investigators

  • Maya Wolf, MD · 1Department of Obstetrics & Gynecology, Galilee Medical Center, 2Faculty of Medicine in the Galilee, Bar Ilan University, Nahariya, Israel

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • Israel

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02819570 on ClinicalTrials.gov