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Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane

NCT01503606 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 151

Last updated 2022-04-20

No results posted yet for this study

Summary

The purpose of this study is to compare the neonatal outcome and infant neurologic outcome whose mother were treated with cefazolin plus clarithromycin for one week or until delivery after preterm premature rupture of membrane.

Conditions

  • Preterm Premature Rupture of Membrane

Interventions

DRUG

Cefazolin

Cefazolin 1.0gm IVs q 12 hours after randomization for one week

DRUG

Clarithromycin

clarithromycin 500mg po bid after randomization for one week

DRUG

Cefazolin

Cefazolin 1.0gm IVs q 12 hours after randomization until delivery

DRUG

Clarithromycin

clarithromycin 500mg po bid after randomization until delivery

Sponsors & Collaborators

  • Samsung Medical Center

    lead OTHER

Principal Investigators

  • Soo-young Oh, MD, PhD · Samsung Medical Center, Sungkyunkwan University School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-10-31
Primary Completion
2020-12-31
Completion
2021-12-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01503606 on ClinicalTrials.gov